In depressed people, the small amount neurotransmitters problematic. On the one hand, there will not be enough to bind to neurotransmitter receptors in the postsynaptic neuron that is to say that the nerve impulse is not transmitted, but more importantly, we observe that, for the sake of economy, the presynaptic neuron will recapture neurotransmitters too quickly, leaving no nerve impulses move properly.
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